CHE-Alaska Presents, Kids and Chemicals: PFAS exposure and the metabolism



For June’s CHE-Alaska webinar, we were joined by Dr. Jesse Goodrich, Assistant Professor of Population and Public Health Sciences at the University of Southern California. Dr. Goodrich discussed a recent study he co-authored which examined PFAS exposure with alterations in metabolic pathways in adolescents and young adults.

The multi-cohort study is the first study to comprehensively examine effects of exposures to PFAS mixtures on human metabolisms. PFAS (Per- and polyfluoroalkyl substances) are man-made chemicals used in numerous consumer products such as food packaging, textiles, apparel, and non-stick cookware due to their stain, grease, and water resistance properties.

PFAS are linked to adverse health outcomes, including liver and kidney damage, reproductive and developmental harm, immune system impairment, and certain cancers. The toxic class of chemicals have been around since the 30s, and due to their persistence in the environment have been dubbed as “forever chemicals”.

PFAS exposure during key developmental periods (such as adolescence or childhood) is a larger concern because of important metabolic tissue growth. During this crucial period, cells become specialized to carry out distinct functions. Examining the effects of PFAS on metabolisms is key to fully comprehending consequences of exposure.

CHE-Alaska is part of CHE’s broader network, which is an international partnership of almost 5,000 individuals and organizations in 87 countries and all 50 US states committed to addressing environmental impacts on human health across the lifespan. We encourage you to become a CHE partner so you can receive their monthly email newsletters, announcements about upcoming webinars, and other updates on a range of environmental health topics. Visit to learn more.

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Jesse obtained his PhD in the Integrative Physiology department at the University of Colorado Boulder. During his PhD, he performed a variety of interventional and observational human research studies examining factors related to glucose metabolism and cardiorespiratory fitness. Jesse’s current research focuses on using metabolomic measures to understand the biological mechanisms underlying the relationship between exposure to persistent organic chemicals and susceptibility to Type 2 diabetes in children and young adults.

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