Differential gene expression and developmental pathologies associated with persistent organic pollutants in sentinel fish in Troutman Lake, Sivuqaq, Alaska

Persistent organic pollutants (POPs) are lipophilic compounds that bioaccumulate in animals and biomagnify within food webs. Many POPs are endocrine disrupting compounds that impact vertebrate development. POPs accumulate in the Arctic via global distillation and thereby impact high trophic level vertebrates as well as people who live a subsistence lifestyle. The Arctic also contains thousands of point…

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Diffusive fluxes of persistent organic pollutants between Arctic atmosphere, surface waters and sediments

Arctic communities are disproportionately exposed to pollutants from sources including global atmospheric transport and formerly used defense sites (FUDS). The effects of climate change and increasing development in the Arctic have the potential to exacerbate this problem. Yupik People of Sivuqaq, or St Lawrence Island, Alaska are one such community with documented exposures to pollutants from FUDS, and their…

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Elevated mercury and PCB concentrations in Dolly Varden (Salvelinus malma) collected near a formerly used defense site on Sivuqaq, Alaska

Sivuqaq’s proximity to Russia made it a strategic location for U.S. military defense sites during the Cold War. Our results suggest that the Northeast Cape FUD site remains a significant point source of mercury and PCB pollution and contributes to higher concentrations in resident fish, including subsistence species. Moreover, elevated Hg and PCB levels in…

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Legacy and emerging semi-volatile organic compounds in sentinel fish from an arctic formerly used defense site in Alaska

The purpose of this study was to investigate the extent of contamination from military operations on Alaska’s St. Lawrence Island (Sivuqaq) through the analysis of sentinel fish, the ninespine stickleback (Pungitius pungitius), collected from Troutman Lake located within the watershed of a formerly used defense site and adjacent to the Yupik community of Gambell. The…

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Threats to Drinking Water and Public Health in Alaska – The Scope of the PFAS Problem, Consequences of Regulatory Inaction, and Recommendations

This investigative report informs actions to address the public health crisis caused by PFAS contamination. In Alaska, the dispersive use of AFFF (aqueous film forming foam) on military bases and airports has contaminated the drinking water of communities from the North Slope to SE Alaska. PFAS have been discovered at over 100 individual sites (mostly…

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Endocrine disruption and differential gene expression in sentinel fish on St. Lawrence Island, Alaska: Health implications for indigenous residents

We investigated polychlorinated biphenyls (PCBs) profiles and endocrine disruption in Alaska blackfish and ninespine stickleback living in the vicinity of the Northeast Cape formerly used defense (FUD) site on St. Lawrence Island in the Bering Sea. FUD sites are point sources of PCB pollution; the Arctic contains thousands of FUD sites, many co-located with indigenous…

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Persistent organochlorine pesticide exposure related to a formerly used defense site on St. Lawrence Island, Alaska: data from sentinel fish and human sera

This study examined whether the Northeast Cape FUDS is a source of exposure to organochlorine pesticides. A total of 71 serum samples were collected during site remediation from volunteers that represented three geographic regions of Sivuqaq (St. Lawrence Island). We found elevated levels of pesticides associated with the former military site in the environment and…

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Contaminants at Arctic formerly used defense sites

This study found elevated levels of contaminants from the military site at Northeast Cape in sediments and plants, including mercury, mirex and other pesticides, and PCBs. Through congener-specific analysis, we were able to distinguish contaminants from the military sites in the region from those accumulated through long-range transport.

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